One of the goals of your child's type 1 diabetes treatment is to keep blood sugar (glucose) levels within the target range determined by their healthcare team.
When the blood sugar level is below 70 mg/dL, your child has hypoglycemia (low blood sugar). Low blood sugar is a possible side effect
of Humalog® that may be severe and cause unconsciousness (passing out), seizures, and death. Test your child's blood sugar levels as their healthcare team instructs.
Possible causes of low blood sugar
Low blood sugar can be caused by several different things:
- Being more physically active than usual
- Skipping or not finishing meals or snacks
- Taking too much insulin, like Humalog. Low blood sugar is the most common side effect of Humalog
- Other medications your child may be taking in addition to insulin
- A combination of these or other factors
Symptoms of low blood sugar
If your child with type 1 diabetes is experiencing low blood sugar, he or she might feel hungry, tired, shaky, sweaty, irritable, headachy, or have other symptoms. Low blood sugar can
include any combination of these symptoms and/or others not listed. And they might not be the same every time. Your child might feel differently depending on how low their blood
sugar gets or on other factors, like what caused their blood sugar to go low. Some children with type 1 diabetes may have no symptoms, so it is important to check your child's blood sugar
regularly as their healthcare team instructs. Know your child's symptoms of low blood sugar.
Low blood sugar can be especially challenging for young children with type 1 diabetes because they may not understand what's happening to their bodies. They may also lack the verbal
communication skills to communicate their symptoms. You should be alert to any symptoms and check your child's blood sugar regularly and when in doubt.
Nighttime low blood sugar
The possibility of nighttime low blood sugar can be nerve-wracking, but eventually you can get to a point where you know what to watch out for and the best ways to reduce the risk.
Be sure to discuss with your healthcare team if your child has nighttime lows.
What can cause it?
Nighttime low blood sugar can be caused by several different things:
- High activity levels during the day
- Physical activity before bedtime
- Taking too much insulin later in the evening. This can lower blood sugar levels even after going to sleep
- A combination of these or other factors
Nighttime low blood sugar while asleep
These are some nighttime low blood sugar symptoms that children with type 1 diabetes might experience while asleep:
- Cold sweats
- A combination of these or other factors
Treating low blood sugar
You should always carry something to treat your child's low blood sugar. If it's mild to moderate, it's usually manageable. Low blood sugar should be treated quickly. If severe, low blood sugar can cause unconsciousness (passing out), seizures,
and death. Below are recommendations for treating mild to moderate low blood sugar. Information for treating severe low blood sugar can be found on the Treating Severe Lows page.
The American Diabetes Association recommends you do the following immediately if your child with type 1 diabetes is experiencing symptoms of low blood sugar:
- Check their blood sugar level. Remember, below 70 mg/dL is too low
- Give your child something containing 15 grams of carbohydrates right away to quickly raise their blood sugar level
- - Some examples include 3 glucose tablets, ½ cup of fruit juice, or 15 small, sugary, chewable candies (eg, jelly beans)
- - Check food nutrition labels to ensure that your child is getting the right amount of carbohydrates
- After 15 minutes, check your child's blood sugar again
- Repeat treatment with carbohydrates if necessary. If your child's blood sugar is still low after another 15 minutes, call your child's doctor or emergency service
After you have treated your child's low blood sugar, be sure they eat regular meals and snacks.
These are guidelines only. Please discuss recommendations specific to your child's low blood sugar with your child's healthcare team.
Important Safety Information for Humalog
What is the most important information I should know about Humalog?
- Do not change the insulin you use without talking to your healthcare provider. Doses of oral antidiabetic medicines may also need to change if your insulin is changed.
- Test your blood sugar levels as your healthcare provider instructs.
- When used in a pump, do not mix Humalog with any other insulin or liquid.
Who should not take Humalog?
- Do not take Humalog if your blood sugar is too low (hypoglycemia) or if you are allergic to insulin lispro or any of the ingredients in Humalog.
Before using Humalog, what should I tell my healthcare providers?
Tell your healthcare providers:
- About all of your medical conditions, including liver, kidney, or heart problems.
- If you are pregnant or breastfeeding.
- About all the medicines you take, including prescription (especially ones commonly called TZDs [thiazolidinediones]) and non-prescription medicines, vitamins, and herbal supplements.
How should I use Humalog?
- Humalog is a rapid-acting insulin. Take Humalog within fifteen minutes before eating or right after eating a meal.
- Always make sure you receive the correct type of Humalog from the pharmacy.
- Do not use Humalog if it is cloudy, colored, or has solid particles or clumps in it.
- Do not mix Humalog with insulin other than NPH when using a syringe. Do not mix or dilute Humalog when used in a pump.
- Inject Humalog under your skin (subcutaneously). Never inject into a vein or muscle. Change (rotate) your injection site with each dose. Make sure you inject the correct insulin and dose.
- Depending on the type of diabetes you have, you may need to take Humalog with a longer-acting insulin or with oral antidiabetic medicines.
- If you forget to take your dose of Humalog, your blood sugar may go too high (hyperglycemia), which can lead to serious problems like loss of consciousness (passing out), coma, or even death.
- Your insulin dose may need to change because of illness, stress, other medicines you take, change in diet, or change in physical activity or exercise.
What are the possible side effects of Humalog?
- Low blood sugar is the most common side effect. There are many causes of low blood sugar, including taking too much Humalog. It is important to treat it quickly. You can treat mild to moderate low blood sugar by drinking or eating a quick source of sugar right away. If severe, low blood sugar can cause unconsciousness (passing out), seizures, and death. Symptoms may be different for each person. Be sure to talk to your healthcare provider about low blood sugar symptoms and treatment.
- Severe life-threatening allergic reactions (whole-body reactions) can happen. Get medical help right away if you develop a rash over your whole body, have trouble breathing, have a fast heartbeat, or are sweating.
- Reactions at the injection site (local allergic reaction) such as redness, swelling, and itching can happen. If you keep having skin reactions or they are serious, talk to your healthcare provider. Do not inject insulin into a skin area that is red, swollen, or itchy.
- Skin may thicken or pit at the injection site (lipodystrophy). Do not inject insulin into skin with these types of changes.
- Other side effects include low potassium in your blood (hypokalemia), and weight gain.
- Serious side effects can include:
- - swelling of your hands and feet
- - heart failure when taking certain pills called thiazolidinediones or “TZDs” with Humalog. This may occur in some people even if they have not had heart problems before. Tell your healthcare provider if you have shortness of breath, swelling of your ankles or feet, or sudden weight gain, which may be symptoms of heart failure. Your healthcare provider may need to adjust or stop your treatment with TZDs or Humalog.
- These are not all of the possible side effects. Ask your healthcare providers for more information or for medical advice about side effects.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.
How should I store Humalog?
- Unopened Humalog should be stored in a refrigerator and can be used until the expiration date on the carton or label.
- Humalog should be stored away from light and heat. Do not use insulin if it has been frozen.
- Opened vials should be kept at room temperature or in a refrigerator. Opened cartridges or prefilled pens should be kept at room temperature.
- Once opened, Humalog vials, prefilled pens, and cartridges should be thrown away after 28 days.
Humalog is available by prescription only.
For additional information, talk to your healthcare providers and please click to access Full Prescribing Information and Patient Prescribing Information.
Please see Instructions for Use that accompany your pen.
HI CON ISI 29MAR2013
Humalog® and Humalog® KwikPen™ are registered trademarks of Eli Lilly and Company and are available by prescription only.
Humalog® KwikPen™ is a registered trademark of Eli Lilly and Company and is available by prescription only.
HumaPen® LUXURA™ is a registered trademark of Eli Lilly and Company. HumaPen® LUXURA™ HD is available by prescription only.
D-Tron® and D-Tronplus® are registered trademarks of Roche Diagnostics GmbH.
Other product names mentioned herein are the trademarks of their respective owners.
Important Safety Information for Glucagon
What is the most important information I should know about glucagon?
- Glucagon should not be used if you have pheochromocytoma or if you are allergic to glucagon.
- Make sure you tell your healthcare provider if you have been diagnosed with or have been suspected of having an insulinoma as glucagon should be used cautiously in this situation.
- You and anyone who may need to help you during an emergency should become familiar with how to use glucagon before an emergency arises. Read the Information for the User provided in the kit.
- Make sure that your relatives or close friends know that if you become unconscious, medical assistance must always be sought. If you are unconscious, glucagon can be given while awaiting medical assistance.
- Do not use the kit after the date stamped on the bottle label.
- If you have questions concerning the use of this product, consult a doctor, nurse or pharmacist.
WARNING: YOU MAY BE IN A COMA FROM SEVERE HYPERGLYCEMIA (HIGH BLOOD GLUCOSE) RATHER THAN HYPOGLYCEMIA. IN SUCH A CASE, YOU WILL NOT RESPOND TO GLUCAGON AND REQUIRE IMMEDIATE MEDICAL ATTENTION.
Who should not use glucagon?
Glucagon should not be used if you have pheochromocytoma or if you are allergic to glucagon.
What should I tell my doctor before taking glucagon?
Tell your doctor about all of your medical conditions and prescription and over-the-counter drugs. Tell your doctor if you have been diagnosed with or have been suspected of having pheochromocytoma or an insulinoma.
How should I use glucagon?
- Act quickly. Prolonged unconsciousness may be harmful.
- Make sure your family and friends know to turn you on your side to prevent choking if you are unconscious.
- The contents of the syringe are inactive and must be mixed with the glucagon in the accompanying bottle immediately before giving injection. Do not prepare Glucagon for Injection until you are ready to use it.
- Glucagon should not be used unless the solution is clear and of a water-like consistency.
- The usual adult dose is 1 mg (1 unit). For children weighing less than 44 lb (20 kg), give 1/2 adult dose (0.5 mg). For children, withdraw 1/2 of the solution from the bottle (0.5 mg mark on syringe). Discard unused portion.
- You should eat as soon as you awaken and are able to swallow. Inform a doctor or emergency services immediately.
What is some important Information I should know about Low Blood Sugar (Hypoglycemia)?
- Early symptoms of low blood sugar include: sweating, drowsiness, dizziness, sleep disturbances, palpitation, anxiety, tremor, blurred vision, hunger, slurred speech, restlessness, depressed mood, tingling in the hands, feet, lips, or tongue, irritability, lightheadedness, abnormal behavior, inability to concentrate, unsteady movement, headache, and personality changes. These symptoms may be different for each person and can happen suddenly.
- If your low blood sugar is not treated, you may progress to severe low blood sugar that can include: disorientation, seizures, unconsciousness, and death
- Low blood sugar symptoms should be treated with a quick source of sugar which should always be carried with you. If you do not improve or you are unable to take a quick source of sugar, you should be treated with glucagon or with intravenous glucose at a medical facility.
What are the possible side effects of glucagon?
- Severe side effects are very rare, although nausea and vomiting may occur occasionally.
- A few people may be allergic to glucagon or to one of the inactive ingredients in glucagon, or may experience rapid heart beat for a short while.
- If you experience any other reactions which are likely to have been caused by glucagon, please contact your doctor.
You are encouraged to report negative side effects of Prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.
How should I store glucagon?
- Before dissolving glucagon with diluting solution, store the kit at controlled room temperature between 20° to 25°C (68° to 77°F).
- After dissolving glucagon with diluting solution, use immediately. Discard any unused portion. Glucagon should be clear and of a water-like consistency at time of use.
For more safety information, please click to access Information for the User and Information for the Physician.
HI GLUC CON ISI 21APR2011
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